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传染病之伤寒ppt课件

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传染病伤寒ppt 伤寒 PPT课件 伤寒PPT课件 传染病之伤寒 伤寒课件PPT幻灯片
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This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 传染病传染病 Infective diseasesInfective diseases This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. • 伤寒病 • 细菌性痢疾 • 阿米巴痢疾 消化道传染病消化道传染病 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 学习习要点 • 传染源: 病人与带菌者 • 传播途径:水与食物的污染,粪—口途径 • 发病机制: 病原体→肠道→肠道症状 ↓ 血液→全身症状 • 病理学诊断: 肠道部位+特征性溃疡+病变性质 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 伤伤寒病 Typhoid Fever • 由伤寒杆菌引起的急性肠道传染病 • 病变特征:全身单核巨噬细胞系统增生 回肠末段回肠末段淋巴组织病变最明显 n 临床特征 稽留高热 神志淡漠 相对缓脉 肝脾肿大 皮肤玫瑰疹 中性粒C和嗜酸性C少 P333 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. • • 稽留稽留热热热热 体温恒定地维持在39-40 oC以上的高 水平,达数天或数周,24h内体温波动 范围不超过1 oC,常见于大叶肺炎、 斑疹伤寒及伤寒高热期。 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 一、病因一、病因 • • 致病菌致病菌: : 伤寒杆菌(沙门菌属),伤寒杆菌(沙门菌属),G G((- -)) ØØ菌体菌体““O”O”抗原抗原 ØØ鞭毛鞭毛““H”H”抗原抗原 ØØ表面表面“Vi“Vi””抗原抗原 • • 致病因素致病因素: : 菌体裂解释放菌体裂解释放内毒素内毒素 无荚膜,无芽胞,无荚膜,无芽胞,有鞭毛有鞭毛 肥达氏反应肥达氏反应------ 临床辅助诊断意义临床辅助诊断意义 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 一、病因 • 传传染源:伤伤寒患者或带带菌者 • 传传播途径: 细菌随粪、尿排出,污染食品、饮用水和牛奶等 或以苍蝇为 媒介污污染食品经口入消化道而感染 • 人群易感性: 普遍易感,病后免疫力比较稳固,很少再感染。 一般以儿童及青壮年患者多见见。 全年均可发病,以夏秋两季最多。 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 二、发病机制二、发病机制 伤寒杆菌(病人或带菌者) ↓经口 (回肠末段)小肠粘膜 ↓ 集合、孤立淋巴小结(致敏) ↓ 血液←胸导管←肠系膜淋巴结 ↓菌血症 单核巨噬C系统C吞噬并繁殖+胆囊内繁殖 ↓菌和毒素入血 败血症 → → → →→ →变态反应 潜伏期(10天) ↑ ↑再次入肠 ↑ 持续高热、相对缓脉、玫瑰疹… 坏死、溃疡 肝、脾、淋 巴结肿大 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 发发病机制中的要点 n n 已致敏回肠末端集合淋巴小结再次接触已致敏回肠末端集合淋巴小结再次接触伤寒伤寒 杆菌杆菌发生坏死发生坏死→→溃疡溃疡, , 溃疡形态应有何特点溃疡形态应有何特点? ? 集集 合合 淋淋 巴巴 小小 结结 孤立淋巴小结 正常回肠末段模式图 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 三、病变三、病变 • 性质:急性增生性炎 ─全身单核巨噬细胞系统的 巨噬细胞增生巨噬细胞增生 ↓吞噬伤寒杆菌、RBC ↓淋巴细胞、坏死细胞碎片 伤寒细胞伤寒细胞 ↓聚集成团 伤寒小结伤寒小结 伤 寒 细 胞 巨 噬 细 胞 伤 寒 小 结 (伤寒肉芽肿) 诊断意义 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 伤伤 寒 肉 芽 肿肿 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. ØØ伤寒细胞伤寒细胞 吞噬吞噬伤寒杆菌伤寒杆菌、、RBCRBC、淋、淋 巴细胞、坏死细胞碎片的巴细胞、坏死细胞碎片的 巨噬细胞巨噬细胞 ØØ伤寒小结伤寒小结 伤寒细胞聚集成团,形伤寒细胞聚集成团,形 成小结节成小结节 ØØ病灶无中性粒细胞浸润病灶无中性粒细胞浸润 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. ØØ伤寒细胞伤寒细胞 吞噬吞噬伤寒杆菌伤寒杆菌、、RBCRBC、、 淋巴细胞、坏死细胞碎片淋巴细胞、坏死细胞碎片 的的巨噬细胞巨噬细胞 ØØ伤寒小结伤寒小结 伤寒细胞聚集成团,形伤寒细胞聚集成团,形 成小结节成小结节 ØØ病灶无中性粒细胞浸润病灶无中性粒细胞浸润 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 伤寒小结伤寒小结 伤寒细胞伤寒细胞 伤寒小结伤寒小结 ----伤寒细胞伤寒细胞聚集成团聚集成团 ,,形成小结节形成小结节 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 肠道病变肠道病变 部位部位: : 最常见于最常见于回肠末段集合和孤立淋巴小结回肠末段集合和孤立淋巴小结 典型病变过程分典型病变过程分4 4期期 ØØ髓样肿胀期髓样肿胀期 W1W1( (第第1 1周周) ) ØØ坏死期坏死期 W2W2 ØØ溃疡期溃疡期 W3W3 ØØ愈合期愈合期 W4W4 临床:体温呈梯形变化。临床:体温呈梯形变化。 粪便菌培养:第粪便菌培养:第2 2周起(周起(+ +),第),第3-53-5周阳性率周阳性率85% 85% 。。 三、病变三、病变 食欲减退、腹部不适食欲减退、腹部不适 、、腹胀、便秘或腹泻腹胀、便秘或腹泻 及右下腹轻压痛及右下腹轻压痛 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. • 回肠肠下段淋巴组织组织 • 以集合淋巴小结结最为为典型 • 圆圆形或椭圆椭圆 形 • 脑脑回样样隆起 • 凸出于粘膜表面 • 灰红红色,质软质软 髓样肿胀样肿胀 期(第1周) 正常髓样肿胀期 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 镜下:肠壁淋巴组织内有伤寒小结形成,肠壁充血水肿 ,粘液分泌↑ This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 坏死期坏死期 ( (第第2 2周周) ) 髓样肿胀处样肿胀处 中心部肠肠粘膜发发生坏死 坏死期髓样肿胀期 变态反应 中央缺血 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 溃疡期溃疡期( (第第3 3周周) ) 坏死肠粘膜脱落→溃疡 • 边缘边缘 隆起,底部不平 • 长轴长轴 与肠肠的长轴长轴 平行 (集合淋巴小结) • 小而圆圆 (孤立淋巴小结) • 溃疡较溃疡较 深 →→ 穿孔、出血 坏死期 溃疡期 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 镜下:可见溃疡,坏死物,伤寒小结 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 肠穿孔 溃疡一般深达粘膜下层,重者达肌层或浆膜层, 甚至穿透浆膜→穿孔。 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 愈合期(第4周) 愈合期 溃疡期 • 肉芽组织增生填补溃疡,上皮再生—愈合 • 较大病灶——瘢痕修复(不易致肠狭窄) This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. n n 典型病变过程分典型病变过程分4 4期期 ØØ髓样肿胀期髓样肿胀期( (第第1 1周周) ) 灰红、质软、脑回状灰红、质软、脑回状, ,以以集合淋巴小结最明显集合淋巴小结最明显 ØØ坏死期坏死期 ( (第第2 2周周) ) 肿胀淋巴肿胀淋巴小小结结中心中心坏死坏死 ØØ溃疡期溃疡期( (第第3 3周周) ) 椭圆形,边缘隆起,底不平,椭圆形,边缘隆起,底不平, 溃疡长轴与肠道长轴溃疡长轴与肠道长轴平行平行 ØØ愈合期愈合期( (第第4 4周周) ) 溃疡底长出肉芽组织,填平、边缘上皮再生溃疡底长出肉芽组织,填平、边缘上皮再生 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 正常愈合期髓样肿胀期 坏死期 溃疡期 淋巴组织增生 肿胀似脑回状 变态反应 中央缺血 溃疡长轴与 肠道长轴平行 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 髓样肿胀期 坏死期 溃疡期 淋巴组织增生 肿胀似脑回状 变态反应 中央缺血 溃疡长轴与 肠道长轴平行 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 髓样肿胀期 坏死期 溃疡期 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 其它单核巨噬细胞系统病变其它单核巨噬细胞系统病变 肠系膜淋巴结、肝、脾、骨髓肠系膜淋巴结、肝、脾、骨髓 ØØ大体大体: :组织组织/ /器官体积增大器官体积增大 ØØ镜下镜下: :伤寒小结和灶性坏死伤寒小结和灶性坏死 三、病变三、病变 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. n n 其它脏器病变其它脏器病变 胆囊胆囊: : 细菌(细菌(+ +)炎症轻)炎症轻 肌肉肌肉: : 膈肌、腹直肌和股内收肌常发生膈肌、腹直肌和股内收肌常发生凝固性坏死凝固性坏死 (亦称蜡样变性)(亦称蜡样变性) 肾脏肾脏: : 肾小管上皮细胞水肿,免疫复合物肾炎肾小管上皮细胞水肿,免疫复合物肾炎 尿培养第尿培养第3-43-4周阳性率周阳性率25%25% 心肌心肌: : 水肿,甚至坏死,可出现中毒性心肌炎水肿,甚至坏死,可出现中毒性心肌炎 皮肤皮肤: : 皮肤皮肤CapCap细菌栓塞细菌栓塞→→玫瑰疹玫瑰疹 ↓ 相对缓脉 三、病变三、病变 →带菌者 →肌痛和皮肤知觉过敏 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 相对缓脉相对缓脉 发热时心率加快,体温每上升1oC ,心率约增加18 次/min。心率的增加落后于体温的上升称相对缓脉 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 玫瑰疹 直径2~4mm淡红红色丘疹,压压之退色,见见于胸腹部皮 肤 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 四、临床病理联系四、临床病理联系 • 体温:升高至40℃± • 肥达氏反应应: – 无特异性,只具辅辅助诊诊断意义义 – 2W±开始出现阳性,可持续数月 – 抗O抗体凝集效价1∶80或以上 – 抗H抗体凝集效价1∶160或以上 • 血、粪粪、骨髓细细菌培养 – 第1~2w血、骨髓培养(+)—败败血症 – 第3~4w粪粪培养(+)—肠肠粘膜溃疡溃疡 形成,坏死物脱 落 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 肥达氏反应应 血培养:病程第1一2周的阳性率最高(80%一90%) 粪便菌培养:第2周起(+),第3-4周阳性率较高 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 四、临床病理联系四、临床病理联系 伤寒杆菌伤寒杆菌 ↓ ↓ 菌血症菌血症 → →胆囊内繁殖胆囊内繁殖 ↓ ↓ 单核巨噬单核巨噬C C系统系统C C吞噬并繁殖吞噬并繁殖 → →伤寒小结伤寒小结 败血症败血症 肝、脾、淋巴结肿大肝、脾、淋巴结肿大 骨髓造血骨髓造血↓→↓→中性粒中性粒C↓C↓ 稽留高热稽留高热 神志淡漠神志淡漠 心肌变质心肌变质→→中毒性心肌炎中毒性心肌炎→→相对缓脉相对缓脉 皮肤皮肤CapCap细菌栓塞细菌栓塞→→皮肤玫瑰疹皮肤玫瑰疹 肠粘膜 坏死、 脱落及 溃疡 随胆汁进 入肠道 食欲减退、腹胀食欲减退、腹胀 、便秘或腹泻、便秘或腹泻… … 粪便细菌培养粪便细菌培养(+)(+) 血培养细菌培养血培养细菌培养(+)(+) This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 结结局和并发发症 • 结结局: 一般4-5周可痊愈。 败败血症、肠肠出血、肠肠穿孔是本病主要死亡原因 • 并发发症: – 肠肠出血 →→ 出血性休克, 肠肠穿孔 →→ 弥漫性腹膜炎 – 支气管肺炎 – 其他,如肾肾功衰竭,骨髓、脑脑膜、关节节感染 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 肠伤寒 • 溃疡形成的原因? • 病理学诊断肠伤寒的依据? • 溃疡形成后,可能出现的后果有哪些? This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 肠伤寒与肠结核之溃疡有何不同? This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m sensor. 肠伤寒 肠结核 部位 回肠下段 回盲部 病变 增生性炎 增生为主 溃疡型、增殖型 肉眼 边缘高起 边缘鼠咬状 与淋巴组织分布相似 长轴与肠长轴平行
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