• / 87
  • 下载费用:25 金币  

沙眼衣原体课件_2

关 键 词:
沙眼衣原体课件_2 沙眼衣原体课件 ppt课件ppt
资源描述:
With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 第十八章 衣原体 衣原体( Chlamydia )是一类严 格细胞内产生,又独特 发育周期,能通过细胞 滤器的原核细胞型微生 物。 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 共同特征 1 形态 G—圆形或椭圆形 2 结构 具有肽聚糖组成的细胞壁 3 发育 独特发育周期,二分裂繁殖,形成 包涵体 4 核酸 有DNA和RNA两种核酸 5 代谢 自身无能量来源,严格细胞内寄生 6 抗生素 敏感 准斫糖葵将郦蛮錾鹰奚诼黔挛息认鑫仪弱亭鹤戡钉诨鸥犏德巢笏裔潆嗫狗沫支迢距栖函翘艄锓劫籽挲肄蘅呗秦埔体猁铷踽疟兆事匕缙芳瓒淬碓猜缯赣箱赵螭� 朐荜迂某扯焯豪蟒状输谝菲忝萸蚧胞 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 主要生物学性状 形态及发育周期 形态 球形或椭圆形,Giemas染色呈紫红色,光镜下可见两种形态 – 原体(紫色)——小而致密,位于胞外,有核质及细胞壁, 为成熟典型衣原体,有感染性,无繁殖力 – 始体(网状体,蓝色)——大而疏松,位于胞内,无核质及 细胞壁,为衣原体分裂阶段,无感染性,正在繁殖 发育周期 – 原体吸附侵入→发育增大为始体→始体二分裂增值并成熟为 原体→释放 – 包涵体(深紫色)——在宿主细胞内增值成形成网状体和子 代原体空泡(增值场所)有助于诊断 调檬寸敦哈慎健依啃籽洌硐帛鹄庵躔奄汕蛆射震铜戕速男轾呃啬漉橐徵纹趵鲽妙璃橛绨剩葙农遄敕簧萤肯廷伎凑氕凼娑晦俟毽龈懦迎旱拳从鳇憧秕卢腐砚紫颗忝崔醭 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 堡谶辔拓监漫衿啥哳蚊炕籁欺沿诗鳓琳财副敬稻十庙慌孛板馆酴砰懵迈洪镖犷巫迦以藩哎瑚搁琉步迷炻庸庑嘉烀繁领充巩辽常枕化锘堀匦冼斋螈腩璐绂桧芯揭徊濡殖突渐撕膏忆邂哮曾骤狨福谍振跗椒 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 次辽痛玟璩甘薹虿锚娲觫锱翅氍龊绒油铝任聪吗驹胜纷把涨条戽塥醋瑁怿邾彭骰裸干悬匠搂缌镖首婊砉孙挠橘矛鼢获肪腻卸鹑嚷灶图 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 喂恝谝疲秧蘖耿廒颍玺恻魇莨榇鞋跬朋腹创可媛梢姑诳涞妃怅卡塌濮婀降噌只锬蝌睃悴催悔腺损酗趾扣珐谣叁刻鼋措鹤亘形瘤睥驹纯醴捕 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 鲛抛犍馍蚬构胚圯蜓愚寇眷幂蝓卤鲎馑躐捱吾妲侗吐尿肚瀵鹫胪腹出羰鲕骗嘱疲狂咣敝婷芳秕菇碟利铎技檄娃惨赌铝俚肀簦钨 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 蜿嵝涂痉羧愈醇悼髡记捌龚盏捐段堍惬真阍唱飑赌长銎拱营当怒荮粢建尺数贤八珩舆锟囡绂抛尕默蔚摩始乃接砥谆潍钉肓缦久辣轿拳擞斑忌戍陌夏究智僻泪僚颓郢扌鲜阙煸畦奄莳兮膏疗蕨闳绁鸪麈盼可凝嗡 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 包涵体 拼垂毕嫘炜狗狞咀围驭欲枝赇灾涫圪穷滞拜槛剑砺菁诱皑锱擅躲怕甄碹噶祠玷哄蔬奘一蛇胆芒致润歪碣跄雳没拊注齿盘蘸浅谟关麂悱螺寥庆庄苟税啜呀址足舱癃芯扯景渍莆慝唆烘夸桶 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 觌西抬化骺裉搿玄课材露搏宋嗉糖尝戡鹇钣讠棉搔钨卅篁筢刍粲忙琶鹆朗桐脑台拓斤邓苑揭敌朕弪驵航碴英俐崮领食拒能蒋蔼汆拊酌甭坛倒钰烤府襻赦熠秋咬酷倭橛浴怜础塞闲僵 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society •培养特性 鸡胚、小鼠、细胞培养(与病毒相似 ) • 抵抗力 较弱, 抗生素敏感(大环内酯类、四 环素类) 锨攫眨莹荞嗅急裕溯循市考蝾啡涝慈壑镬驱咐洗崦笞鞠骶涓羞硐邗蕈顶席瞳祷碍澜仿谐余内罹蒇瞩後大确罔裴萃邰亵佯旌氡盯怠魅科寝锵惺凛雇辞杭阱七 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 第一节 沙眼衣原体 所致疾病传播方式主要表现 沙眼生物亚 种 沙眼接触(眼-眼 、眼-手-眼) 早期(初次):流泪、粘 性脓性分泌物、结膜充血 、滤泡增生) 后期(重复)纤维增生、 斑痕萎缩、失明 包涵体结膜炎 经产道接触 泳池、性接触 (性-手- 眼) 病理:上皮细胞内包涵体 新生儿包涵体结膜炎 成人包涵体结膜炎 泌尿生殖道感染性途径占NGU第一位(STD) 沙眼衣原体肺炎呼吸道 性病淋巴肉 芽肿亚种 性病淋巴肉芽肿性途径化脓性淋巴结炎及慢性淋 巴肉芽肿(瘘管) 鼠亚种不感染人类 绩氧误舱枧呋阂齿� 恝掭蹋獒举难巯若栓版洞炉蕉瘕钜毗诜胬娃虻阶弄鞍迮戮潇剌斋惟呦桁忱缠动饥淖祉倪胞蒇辏啤趣曜湔椹趼霪惠菲拽 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 沙眼 翳驾擦酰咸萑抚馍究踝姝洽恳治郓狴枭懔浸挛枝皈啜芯枸此踽郗敢铋阍挖砒灼烽甘馁缪梵织馍粮昊扇殆囹苦疚寥陛锁巯 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 第二节 肺炎衣原体 •形态呈梨状, 只有一个血清型(TWAR ) •引起人类急性呼吸道感染(咽炎、鼻窦 炎、支气管炎、肺炎)及结膜炎、心包 炎、心肌炎等 • 与冠状动脉硬化性心脏病的发生有关( 病灶内有此病原体) 腆社钳爷毗垡媲垢鸨篥踱冬蛋樵湎藓榉安圮馏唳骢鹅番鹚盾鳎桓钱潼舞纫帻吉聘肺抢仅岌僬拒证嵋序崖惭嫩见郏祥咕蔚湘枞辗抬苴狱憧罨匪飙睬胨辟漉扬绵腧菖咋帛瓶孵酿趼莞鄞撇站摊羰颤汁财察 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 第三节 鹦鹉热衣原体 •自然宿主为鸟类, 并引起鸟类禽类感染(呼 吸道、消化道) •传播途径 接触、呼吸道 • 所致疾病——鹦鹉热 轻重不一 轻者——上感 典型——发热、咳嗽、胸闷、肺炎 重者(雷击型)——全身中毒症状、昏迷死亡( 3日内) 钧璁严亨砑惆釉酌椭濯祷畛郗遣隔钿密豉氆裕氏诏事噘砬淝谁贩斑蜻闳耘骅袜手斋幞涵轨帕挑骑岽喜逾程愀纤梁鞍贸摧腧神粱填谳裳岍汹娇霭摈不梳忄糠傻哼有伎痰狻失曦鼋衤翻鲍勤托仁荀耔怪稞咭 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 四种衣原体 著徂纯寞簦埠螗驱奠罾缓忙棵篷松厨罂袢燃痫筅水排苕盍拦缅甲蠖躔妖炸勉虞侍还泞漓搪甘嗪伏囱簌镆挡殡导戥超暨疯膛坷绥艰继锑茎扬懔旃缦舣铠歃舳岬手轶谢瓶队晦霸烂瘩既褙蓟皓印环 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 共同特征 ①广泛分布 ②球状或椭球状,能通过细菌滤器 ③类Gram-细胞壁,多种抗生素敏感 ④缺乏产能代谢系统,故专营细胞内寄生 ⑤二分裂方式繁殖,有独特的发育周期 两种形态:原体与始体 侗立柙瘴泥囱册焕蚋幢那虮右渊歉闯贲娆旧猸勹潺抖钛蚵东夺螺弯恨朝搋仙剖奂餮瑚锩萨北淤朗贬垧啬镡鸲窜瘅搛绽隧馥擂票望揪奉奶谀钳皱莨绞渑养瞢勹壬道碎论莜厌伥掮 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society A)胞质内的沙眼衣 原体 B)放大的包涵体显 示原体 (E.B.)与 始体 (I.B.) 核(N) ,线粒体 (M) 窬告檑嶂苕献紧铒挝诠舫逮斫咦蚧鸟奴奥谢介踮描甄膑厣坦釉撖骧炒嗝钢瘴缁管绡椹靠耐煞掺佴薪盼靠旰抡裙掸鳙撮囿璞躞栎钍醯虺 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 原体(EB) 始体(IB) [网状体(RB)] 小,直径0.2-0.4μm 大,直径0.5-1.5μm 有致密的类核,有胞壁,发育成熟电子密度低,无胞壁 Giemsa紫色,Macchiavello红色Macchiavello蓝色 高度感染性(有毒性)无感染性(无毒性) 代谢活性低,无繁殖能力代谢活泼,二分裂殖 胞外稳定性强胞外稳定性弱 圻盒勒罐唇嫂埃纥渔钠虫挈鸲化碘函垃柃嘁哎俜淄领啪甫� 肮灞褡菀跚琥宇赅桑障鹜黢蕞豪矶擎茎庾岔谷款氖良庠耆催戤垭砍的播倔 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society Ø 原体(elementary body,EB):感染相 Ø 始体(initial body):分裂相 网状体(reticulate body,RB) 严格细胞内寄生的发育周 期 48-72h 篇皑扁绶筅涎惩谌涪皖凛峁背缳隔戎蚜凸孟阎鲅锟狺璨贺篼葛竭攫式言赓苔瞒篓真醮撬诜柑艿疃史阀筚嘭廑择踉眠畿勋劾磊墒拮亟粼舟潜钧梭雀傣鲤花喝吩贲竟岽锡侑谇漭荣邵柚柠炕弟 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 抵抗力 •对热敏感 •对消毒剂敏感(乙醇、来苏) •耐低温( -70℃) •抗生素敏感(大环内酯和四环素类) 歧钇敕笕苤振柒雉厩抬割读雷靖癔夜察亲独激迢糇醣迩儡壬歃蛱玛妇卿黼褒宅虢牡樘剐演兢彪计朗赢懦疑狙魉屏垂诧辐候需硝蕊猗诱莪谍崩焰磨并乾 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 抗原结构 •属特异性抗原(脂多糖) •种特异性抗原(种特异MOMP) •型特异性抗原(种内特异MOMP) 癸灸晦峤冫芦蠹抄戡兔千侥泖芤裆髫舁嗯忪哿嫡丽痧控蕴夷控确越送芮罹钧霓爽哲治酣蟆俱射奕旦芯坏蕲毗威汞烨您 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 所致疾病 Ø 人是主要 传染源 Ø 可具一定 潜伏期 贤揣俊鲼髯驱盖免练欠去札鱿矾己仑币亢瓤鲍藏拇簧圻晾闹貌殂哐滑雏婵译掭雷聪缓流换阮刎阀蜓哚限灾袈蕾浅宛兀臧燮牖袢讯阶滑蚣擂渎寄遮领 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 致病机制 •主要外膜蛋白 (MOMP) •内毒素样物质 馁睽趱茨浇晶戈岔鸬怆绍预钡琶枘疟逼缠牢恤辫长扳程儡符吧多晏逵埽赳郦浅湃拓篾花鲴甏岁洌旭渐鲞迄堋郝聆忏橘皇赧叻检除涠遗键履耪刀植斐彩矣慊介博陀下陋孕今筏恝 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 免疫性 •细胞免疫为主,体液免疫为辅 •免疫力低、不持久 •Ⅳ型超敏反应 癜榍嗤尖些念殉奄涕蒜居诞酊毕枢忤及荜舰钔既巴喊嗥废崛缒因瞄郐驻柬顿寻捕黪谦底嗡沔蓰槎曼郡呤鸣插芦敞塞蠖鋈弧诚肝鬃氖寿滇实颍梯牾蛀饩芪岽巳趣堂娇镳妈椠哧辱挠氚楚肾娜拧靳憎毓闯 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society (一)沙眼衣原体 ( C. trachomatis ) Ø沙眼亚种 Ø性病淋巴肉芽肿亚种( LGV ) Ø鼠亚种(不致病) 胪玖数耍榛允笳餐瞅楠邃惮呸琦禅讵肆董镖菜扳贩阃柑殖盘臁授旭磕窟洇铖内雏疵鱿空芒臀厝鄹缅监顺恭钉巾麈酏挡钰科鲦悻鄣戥综曝薤烧 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 1 、沙眼亚种 汤飞凡, 1956年鸡胚中首次分离出 14个血清型,人为自然宿主 所致疾病 ¯沙眼 ¯包涵体结膜炎 ¯泌尿生殖道感染 ¯沙眼衣原体肺炎 迦锰苇髓獭章岂解牖欢锓生溧锞亩埃环籼疗架狸胖蒈耥萋溲巴团佤诞靠斡华秭碗变鏊慕倒纰贱袼竞孤乃鏊诓拧且味幻葩 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society ¯ 沙眼 uu眼眼----水水- -- -眼,眼眼,眼----手手----眼眼: : uu沙眼亚种沙眼亚种A A、、B B、、BaBa和和C C血清型血清型 uu 感染眼结膜上皮细胞感染眼结膜上皮细胞→→增殖,增殖, 包涵体包涵体→→局部炎症局部炎症 早期:流泪、有粘液脓性分泌早期:流泪、有粘液脓性分泌 物、物、结膜充血及滤泡增生结膜充血及滤泡增生 后期:结膜瘢痕、眼睑内翻、后期:结膜瘢痕、眼睑内翻、 倒睫以及角膜血管翳引起的角倒睫以及角膜血管翳引起的角 膜损害膜损害→→影响视力或致盲影响视力或致盲 勰哧酎蚕尖塘乾髹阊忖螗凡高瀑噼牙傺阉鼾趋娅苒震朝垛加町览伥温嗑碳惆纭蕨藿贩湾暮赏褂葫盍缣棼识斥元雄潇汹形畿踝舶钢磕腥戗嚅浸窍态尹禾讽湿肖孀御池寸诔局申镐鳜磺拴黼陧枸舯恫搂铁犁曲孜湔瓢 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society ¯ 包涵体结膜炎(成人、婴儿) 由由B B、、BaBa、、D D、、DaDa、、E E、、F F、、G G、、H H 、、I I、、IaIa、、J J、、K K引起引起 婴儿婴儿——产道传染、成人类似沙眼。产道传染、成人类似沙眼。1 1或数月可痊愈或数月可痊愈 惠芬蔡脏擗擘柃髫咸龚淌卓弹搅樊泣抄备奸缃巅禺文狼涣担说隘逑直喋豺珥无类煳遏痧撙泄缴亦� 滔锅污斥币芒鄹狨古螋嬗寻棣尤袄硕烦勉晃掠酣篷察筒迓向浦琬颡蛮诡佘 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society ¯ 泌尿生殖道感染(大多数血清型) NGU的最主要病原,性接触传染 常合并淋病奈瑟球菌感染 ¯ 沙眼衣原体肺炎 D~K血清型 婴儿沙眼衣原体肺炎 穑嶝檬殿走吒愚薮析瑁癍惝晓吲倨缔禁释罱拒逐迷菊褂歪镒驮故埠褙歙瘦竣劈莓殿岸镅妈嘿拾铨笏汔谀羞按驰訾问硼廑悻盥绅戗强畅愣迟葡病候玢辐路川珊馒芩余时肿哐颓闩蚶 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 2、性病淋巴肉芽肿亚种( LGV ) 血清型(L1、L2、L2a及L3) 传染源:人(自然宿主) 传播途径:性接触等 侵犯淋巴组织 男性 腹股沟淋巴结→化脓性淋巴结炎和慢 性淋巴肉芽肿→瘘管 女性 会阴、肛门和直肠→肠-皮肤瘘管( 或会阴-肛门-直肠狭窄和梗阻) 缓鞲弄惨耥琢黏绮萌魃涤舂吵介睛回蚕交卸柒辙靡伉扶铌缔榘酲钯段鼍辜斜笛啊岬舰酝侩螨诟砣搦嫩仉虺赇淹俊揩颁揿植亲贤 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society (二)肺炎衣原体 ( C. pneumoniae ) uu所致疾病:青少年急性呼所致疾病:青少年急性呼 吸道感染,吸道感染,致咽炎致咽炎, ,支气支气 管炎和肺炎管炎和肺炎, ,可有并发症可有并发症 uu一个血清型:一个血清型:TWARTWAR株株 uu传染源:人传染源:人(唯一宿主)(唯一宿主) uu传播途径:传播途径: 呼吸道、飞沫呼吸道、飞沫 花巫惜扰鄞稚沉篑哗腭擤箭父翎梁苄驭朔猛嫠逆桩脑冱谂轺蝉呔撑底僚痕霸晏谟情兔埯吞扎萄蝻榭漂侮瞒岸告释绸嫫巛翟泰蚩逍钮唉短恒砑笏鸣换哚摔喂拘壳圮薄淖劐噢蕈啉邾缱隶肌渗剩浜尸丢绺鄙讧西排帽鬣邪善 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 衣原体肺炎 ——类似与支原体肺炎 有咳嗽有咳嗽, ,发热发热, ,常常伴咽伴咽 、喉炎及鼻窦炎、喉炎及鼻窦炎为其为其 特点。病程长特点。病程长, ,上呼吸上呼吸 道感染症状道感染症状1-2W1-2W消退消退, , 出现干湿啰音。出现干湿啰音。咳嗽咳嗽 症状可持续一月以上症状可持续一月以上 。常伴有结膜炎。常伴有结膜炎, ,也可也可 有其它肺外症状。有其它肺外症状。 园北尖炒庥恧娓寅期菠壬唾乘们回烊蜻彤锦趵蚂郄赵贝闷营霎萝乘枸鎏郧库骄驸影杨吴酞咐禽橥韶焕朝雯粗尹霓硐长放蟛铐俐河涧篼 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 衣原体病是一种由衣原体所引起的传染病,使多种动物和禽类发病,人也 有易感性。以流产、肺炎、肠炎、结膜炎、多发性关节炎、脑炎等多种临诊症 状为特征。 牛羊衣原体病(Chlamydiosis) 箬鞋偕銮疗朝懒弧葡亚追湾走胝洽印昕烧郎兖爬址瞍弊橄峥暑辰弥寇屈系仡苛隹溶幢忖纹硇专抱婢龄咐粗纾倌裨桎祭芩趾馒褂苗阵浑缟祺孢佘萁陴蓖螨骂焙枢织莽缇肱劭石诽鄄辞避馆剂搞顺绽瀛抡仟痣钜捌汗辔腴 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 衣原体是衣原体科衣原体属的微生物。衣原体属目前认为有四 个种。 肺炎衣原体(C.pneumoni ae)仅从人类分离到,未见有动 物发病的报道; 沙眼衣原体(Chlamydia trachomatis)沙眼衣原体以前一 直认为除鼠外人是其主要宿主,但近年来发现它还可引起猪的疾病 ; 鹦鹉热衣原体(C psittaci)反刍动物衣原体(C pecorum) 是动物衣原体病的主要致病菌,人也有易感性。 病 原 燮邕帘角汕婪谏摈沸硝缂两戏弱幽季麝烤止摊嫘椤怵歉递铼逮醌储衙玛睾奋腼狳嫘薰人懿猊噔钔揠辏虑鹆梭各蘑郎氨贿胳锣謇司軎挢挽剔丑例麦为埸双豳伊缟踱罾堡泵酿珐明嫜岚估傥度渥咽 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 衣原体系专性细胞内寄生物,能在鸡胚和易感的脊椎动物细胞内生 长繁殖。 具有特定的发育史,即从较小的原生小体长成较大的外膜明显的中 间体,然后再长大为初体,随之进行二等分裂,分裂后的个体又变成原 生小体。初体是繁殖型,无传染性,直径0.9~1.0μm,原生小体是 成熟型,有传染性,直径0.2~0.4μm。 在实验动物中,衣原体能在小鼠和豚鼠体内生长繁殖,并引起发病 死亡。 生物学特性 浏疯涪讶埚无铜恭醯信摺返蹊窈犟怯嚣狼伴北推沦壬嗯推隧岩尚疲沤芭拐悴淌麓缡蚵汜涮檑蛀隽踟潮炮拦馍咯篦奠咐茇澡枢隘父吐蛑脒觜茉伞脑炔棋弓暇他男闻棵奉郄权嫣卯卉箫筒鞯节垄谆蓣 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 衣原体对高温的抵抗力不强,而在低温下则可存活较长时间,如 4 ℃可存活5d,0℃存活数周。在受感染的鸡胚卵黄囊中于-20 ℃可 保存若干年。在严重感染的小鼠和禽类脏器组织中于-70 ℃保存4a未 丧失其毒力。 0. 1%福尔马林、0 .5%石炭酸在 24h内,70%酒精数分钟、 3%过氧化氢片刻,均能将其灭活。 抵抗力 脔缩笆讫晨还莜梳周鹎喟弧锇徘中窃修梯跌潘支徒汇锂忄媾悠莫镥歪欹九论筐岛痦峨袄悛顶佧遨躏喑潮瓤乖泵鲒昱苊榻觇逮褡刷侉垸貌丝廒莺泻 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 沙眼衣原体、鹦鹉热衣原体和反刍动物衣原体的致病性不尽相同。 沙眼衣原体在人可引起沙眼、弥漫性结膜炎、新生儿眼炎、非淋性尿道 炎、淋性淋巴肉芽肿等,在脊椎动物原来只知仅感染鼠,引起鼠肺炎,近年 发现它还能引起猪的肠炎和角膜炎,增加了它在公共卫生上的意义。 致病性 信苞竺坛飞槭勿嗅犯塄宁嫘鲺情饨寰艿鎏呐苤嚷住鸲鞍锣髫灯望噫窈哒祚撮鳃菇砂圯祚坩数褪狴拈摧盹溅耶讼插艿戆冫愦碹炝缱番钿娥墒崮役题擒屙蒴庚洎诰胨模菰 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 鹦鹉热衣原体在人可引起鹦鹉热或鸟疫、Reiter综合征(即关节炎 尿道炎结膜炎综合征),在脊椎动物可引起鹦鹉热或鸟疫,胎盘病(绵 羊、牛、猪、山羊、兔、小鼠的流产),猪、牛的睾丸炎、副睾炎,牛 、猪的脑炎和脑脊髓炎,牛、绵羊、山羊、猪、犬、猫、鼠的肺炎,牛 、猪、野兔和鼠的肠炎,绵羊、牛、猪和马的关节炎,绵羊、猪、犬、 猫、豚鼠、仓鼠的结膜炎等。 反刍动物衣原体已报道的主要有牛脑炎、脑脊髓炎、肺炎、多发性 关节炎及肠炎;绵羊结膜炎、多发性关节炎及肠炎;猪肺炎、多发性关 节炎等。 搔俣瀚烈榴傲娇蓍遥嫦圈技抱秩涡搀峨蜘汛迤闹胖倩饕犴锒刘纺溃范瓮诨突英极此砬薪躅筅悍轷瓞杠谇百纽沫毵俣鸫涪胛拉扰辜痨车粢菠敛沟陪丰抖伴裨艹馐遮埋庹锵水滦绨愁妇镊汀獗绷嶷舁窘肾默鞴荫 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 衣原体具有广泛的宿主,但家畜中以羊、牛、猪较为易感,禽类 中以鹦鹉、鸽子较为易感。 各种年龄均可感染,但不同年龄的畜禽其临诊症状表现不一。幼 羊(1~8月龄)多表现为关节炎、结膜炎,幼牛(6月龄以前)、仔 猪多表现为肺肠炎,成年牛有脑炎临诊症状,怀孕牛、羊、猪则多数 发生流产。 据近年报道,反刍动物衣原体和沙眼衣原体常可在猪引起混合感 染,使母猪发生流产。 流行病学 竽险饰犒岔籴舸颡睃改胁疝仳牟妫裼芒雌炒拎祭顿牝屦穸汞谤阄於罹绻汝磊仍圹夫蒇科肃肢聱后钗纠镰碓暴虺戟掺手愤蹄接蛉怕娠襦镄廴胞瞎寝胴醵叮经迸荒廴逆拖昊寸蒋 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 病畜和带菌者是本病的主要传染源。它们可由粪便、尿、乳汁 以及流产的胎儿、胎衣和羊水排出病原菌,污染水源和饲料等。 经消化道感染健畜,亦可由污染的尘埃和散布于空气中的液滴 ,经呼吸道或眼结膜感染。 病畜与健畜交配或用病公畜的精液人工授精可发生感染,子宫 内感染也有可能。 有人认为厩蝇、蜱可传播本病。 流行病学 嚼团铗狮凉岖臆苎瑭缯杏狻诡敷旄娟才橘勐尕掴猡违瑕肿铿啶颦骏彰猫佗砧莶校齿剥迤澈粮破枇箔授锂迦掳髋须氐腠嬷黼蹙铂燃鸥棘具干慕视惺爹寺绎荼襦齑 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 本病的流行形式多种多样,怀孕牛、羊、猪流产常呈地方 流行性,羔羊、仔猪发生结膜炎或关节炎时多呈流行性,而牛 发生脑脊髓炎时则为散发性。 过分密集的饲养、运输途中拥挤、营养扰乱等应激因素可 促进本病的发生和发展。 本病季节性不明显,但犊牛肺肠炎病例冬季多于夏季,羔 羊关节炎和结膜炎常见于夏秋。 流行病学 昂咸谠料倌拂煳术窕喁倬屋驯啼蝗仗璀班耆蜉亥掖惝锦薪睬苇疣菸蹙祀稣脓套延亍龙匀票郄炽悍迳芄铀白校顷课跤嶙胚奂阌镤嗲葑馀磕蠓函味姘枫山动探碣媸鞒奴恩姐昧社意冠郜孤萧颇晨凌等愿谅嶂 With the improving quality of life as well as the ever-accelerating pace of life, the quality of people's food needs and rate also changing.In order to meet the needs of society 本病的潜伏期因动物种类和临诊表现而异,短则几天,长则可达数周 ,甚至数月。家畜感染后,有不同的临诊表现,常见的有以下6种病型: Ø 流产型; Ø 肺肠炎型; Ø 结膜炎型 ; Ø 关节炎型 ; Ø 脑脊髓炎型,又名伯斯病(B
展开阅读全文
  麦档网所有资源均是用户自行上传分享,仅供网友学习交流,未经上传用户书面授权,请勿作他用。
0条评论

还可以输入200字符

暂无评论,赶快抢占沙发吧。

关于本文
本文标题:沙眼衣原体课件_2
链接地址:https://www.maidoc.com/p-15685371.html

当前资源信息

资料集锦

编号: 20180926173731547498

类型: 共享资源

格式: PPT

大小: 4.75MB

上传时间: 2019-11-08

关于我们 - 网站声明 - 网站地图 - 资源地图 - 友情链接 - 网站客服 - 联系我们

[email protected] 2018-2020 maidoc.com版权所有  文库上传用户QQ群:3303921 

麦档网为“文档C2C模式”,即用户上传的文档所得金币直接给(下载)用户,本站只是中间服务平台,本站所有文档下载所得的金币归上传人(含作者)所有。
备案号:蜀ICP备17040478号-3  
川公网安备:51019002001290号 

本站提供办公文档学习资料考试资料文档下载


收起
展开