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组织与胚胎学双语课件_骨与软骨

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组织 胚胎学 双语 课件 软骨
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单击此处编辑母版标 题样式 单击此处编辑母版副标题样式 1 Chapter 4 cartilage and bone Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial Cartilage 软骨 Structure strong basophilic 硫酸软骨素较多 cap Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial LM Peripheral chondrocytes less mature small single Central chondrocytes more mature round isogenous group 同源细胞群 EM rich in RER r Mit developed Gl Glycogen Outer layer more collagenous fibers Inner layer more b v epiglottis etc nStructure elastic fiber dense symphysis pubis end of tendons etc nStructure collagenous fiber A large number in parallel bands less g s inorganic 65 Organic part collagenous fibers 90 amorphous g s GSG HA chondroitin s keratin s Glycoproteins osteocalcin 骨钙蛋白 osteonectin 骨粘连蛋白 osteopontin 骨桥蛋白 Function responsible to resilience 2 Bone matrix 骨基质 Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial Inorganic part bone mineral 骨盐 mainly hydroxyapatite crystal 羟基磷灰石 结晶 with the composition Ca10 PO4 6 OH 2 be responsible to hardness Bone lamellae 骨板 bone matrix arranged in plywood like layers with fibers parallel or in right angles apatite needles lie alongside the fibrils Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 3 Cells Osteoprogenitor cells 骨祖细胞 Osteoblasts 成骨细胞 Osteocytes 骨细胞 Osteoclasts 破骨细胞 Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial A Osteoprogenitor cell 骨祖细胞 Location In periosteum LM cuboidal low columnar polygonal strong basophilic large pale nuclear w obvious nucleolus EM short processes rich in rER processes long fine in canaliculi weak basophilic tissue fluid fills in bone lacunae 骨陷窝 Exchange the Ca 2 b w tissue fluid and blood processes Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial D Osteoclast 破骨细胞 Location In depression on the bone surface termed Howship s lacunae LM Giant cell irregular multinucleate 5 50 fusion of monocytes acidophilic ruffled border 皱褶缘 Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial EM Mv ruffled border ring clear zone w Mf Lysosomes Phagocytosis vacuoles Others Mit rER Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial Function Clear zone 亮区 attached the bone surface to form a microenvironment Osteoclasts release lysosomal enzymes proteinases carbonic anhydrase n4 20 layers of Osteon lamellae Haversian Central canal中央管 b v n f tissue fluid in it canaliculi open to the canals nA cement line 粘合线 wraps around the unit consist of mineralized matrix with few collagenous fibers b Osteon Haversian system 骨单位 Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial nVolkmann s canals perforating canals 穿通管 communicate w the central canals Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial c Interstitial lamellae 间骨板 nIrregular lamellae b w the osteons nIt is the remnants of osteons during reconstruction I L os Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 5 Periosteum 骨外膜 outer layer dense c t thicker the perforating f 穿通 纤维 Sharpey s fibers fix the periosteum to bone inner layer containing osteoprogenitor cells small b v growth repair reconstruction Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial Histogenesis of bone 骨的发生 1 Intramembranous ossification 膜内成骨 parietal bone frontal bone clavicle mesenchymal cells membrane of CT osteoprogenitor cells osteoblast Osteoid osteocyte calcification osseous tissue primary ossification center Primitive bone trabeculae woven bone a layer of spongy bone resorption and remodeling 3 layers inner and outer plates of compact bone and diploe bone in between Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 2 Endochondral ossification 软骨内成骨 1 formation of cartilage model 软骨雏形形成 mesenchymal cell osteoprogenitor cell chondroblast chondrocyte hyaline cartilage tissue perichondrium Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial lmiddle part lInner cells of perichondrium osteoprogenitor cells Osteoblasts secrete bone matrix Lay down bone bone collar on outside of cartilage model l Responsible for increase in width and thickness of diaphysis 2 Formation of bone collar 骨领形成 Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 3 endochondral ossification 1 primary ossification center 初级骨化中心 lPrimary ossification center formed in the center of cartilage model l Chondrocytes hypertrophy Cartilage matrix calcified Chondrocytes die Invasion of blood vessels and mesenchyme cells Removal of calcified cartilage by osteoclasts and formation of primary marrow cavity Osteoblasts lay down primary bone on calcified cartilage matrix remnants Ossification spreads toward the ends lAt this stage the calcified cartilage appears basophilic and the primary bone is eosinophilic transitional trabeculae Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 2 secondary ossification center 次级骨化中心 epiphyseal plate between diaphysis and epiphysis responsible for increase in length of a long bone 4 zones resting cartilage zone proliferating cartilage zone calcified cartilage zone and ossification zone Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial The 4 zones of epiphyseal cartilage showing the continuous process of endochodral ossification 1 resting cartilage zone 2 软骨储备区 small chondrocytes diffuse basophilic cytoplasm 1 1 1 2 2 2 2 3 3 3 3 3 3 3 3 4 4 4 4 4 4 Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 2 Proliferating zone 软骨增生区 chondrocytes proliferate and form columns parallel to the long axis of the bone Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 3 Calcified cartilage zone 软软骨钙钙化区 calcified matrix with dead chondrocytes pyknotic nucleus intensely basophilic matrix Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 4 Ossification zone 成骨区 vdeveloping trabeculaes 过渡性骨小梁 blue in centre red in periphery osteoblast osteoclast vprimary marrow cavity vhematopoietic tissue Five weeks of practice ended in this way and my feelings can only be summed up in eight words although hard but very substantial 3 Bone growth and remodeling 骨的生长和重建 l Bone increase in size from birth into early adulthood due to a combination of bone formation and resorption l Woven bone replaced by lamellar bone at birth l Haversian system appears about 1year after birth and rebuilds during growth and even in adults l Change in curvature of the skull Formation of the osteon
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